Analysis of macromolecular structure and dynamics by electron cryo-microscopy. |
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| Authors: | W Kühlbrandt K A Williams |
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| Affiliation: | Max-Planck-Institute of Biophysics, Department of Structural Biology, Heinrich-Hoffmann-Strasse 7, Frankfurt am Main, D-60528, Germany. kuehlbrandt@biophys.mpg.de. |
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| Abstract: | Electron cryo-microscopy has yielded a wealth of detailed new information on structures of biological macromolecules ranging from alphabeta-tubulin at 3.7 A resolution to hepatitis B virus at 7.4 A resolution, as well as a number of membrane proteins at 6-8 A resolution. Much of this progress was made possible by recent advances in instrumentation and image processing techniques. |
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