| 关于血清 Cu,Zn及 CuZn-SOD 与恶性肿瘤关系的探讨 |
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| 引用本文： | 唐煦,周国林.关于血清 Cu,Zn及 CuZn-SOD 与恶性肿瘤关系的探讨[J].微生物学免疫学进展,1997,25(2):35-37. |
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| 作者姓名： | 唐煦 周国林 |
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| 作者单位： | 兰州铁路局中心卫生防疫站(唐煦)，卫生部兰州生物制品研究所(周国林) |
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| 摘 要： | 本文用原子吸收光度法，Ｏｙａｎｇｕｉ法及ＡｄａｃｈｉＹ法分别测定了正常人与五种肿瘤患者血清Ｃｕ，Ｚｎ含量，铜锌超氧化物歧化酶（ＣｕＺｎ－ＳＯＤ）的活性以及谷胱甘肽硫转移酶（ＧＳＴ）的活性。结果表明：恶性肿瘤患者血清中铜含量升高，锌含量降低，ＣｕＺｎ－ＳＯＤ活性降低，而ＧＳＴ活性在正常人与肿瘤患者间无显著差异（Ｐ＞０．０５）。提示人血清中高铜，低锌，高铜／锌比值，以及ＣｕＺｎ－ＳＯＤ活性降低与恶性肿瘤的发生有关。
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| 关 键 词： | 恶性肿瘤 微量元素 铜锌超氧化物歧化酶 谷胱甘肽硫转移酶 |
Study on Relationship Between Serum Cu,Zn,CuZn SOD and Malignant Tumors |
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| Tang Xu.Study on Relationship Between Serum Cu,Zn,CuZn SOD and Malignant Tumors[J].Progress In Microbiology and Immunology,1997,25(2):35-37. |
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| Authors: | Tang Xu |
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| Abstract: | The level of serum Cu,Zn,and the activity of the CuZn SOD and GST were studied.Results showed that there were higher serum Cu,lower Zn,lower CuZn SOD activity in the patients with malignant tumor and that there was no signficantly different serum GST activity between healthy adults and patients with tumor.It was revealed that higher serum Cu,lower serum Zn,and lower CuZn SOD activity were relevent to the formation of malignant tumors. |
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| Keywords: | Malignant tumors Trace element CuZn SOD GST |
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