TH-17 cells in rheumatoid arthritis |
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Authors: | Shiva Shahrara,QiQuan Huang,Arthur M Mandelin Suffix" >II,Richard M Pope |
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Affiliation: | (1) Department of Medicine, Feinberg School of Medicine, Northwestern University 240 E. Huron, Suite M220, Chicago, IL 60611, USA;(2) Jesse Brown VA Chicago Healthcare System, 820 S. Damon, Chicago, IL 60612, USA |
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Abstract: | Introduction The aim of this study was to quantify the number of T-helper (TH)-17 cells present in rheumatoid arthritis (RA) synovial fluid (SF) and to determine the level of interleukin (IL)-17 cytokine in RA, osteoarthritis (OA) and normal synovial tissue, as well as to examine SF macrophages for the presence of IL-23, IL-27 and interferon (IFN)-γ. |
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