Microfluidic components and bio-reactors for miniaturized bio-chip applications |
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Authors: | Kwang-Seok?Yun Email author" target="_blank">Euisik?YoonEmail author |
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Institution: | (1) Department of Electrical Engineering and Computer Science, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, 305-701 Daejeon, Korea |
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Abstract: | In this paper miniaturized disposable micro/nanofluidic components applicable to bio chip, chemical analyzer and biomedical
monitoring system, such as blood analysis, micro dosing system and cell experiment, etc are reported. This system includes
various microfluidic components including a micropump, micromixer, DNA purification chip and single-cell assay chip. For low
voltage and low power operation, a surface tension-driven micropump is presented, as well as a micromixer, which was implemented
using MEMS technology, for efficient liquid mixing is also introduced. As bio-reactors, DNA purification and single-cell assay
devices, for the extraction of pure DNA from liquid mixture or blood and for cellular engineering or high-throughput screening,
respectively, are presented. |
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Keywords: | DNA chip cell chip MEMS bio chip micropump micromixer |
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