Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation |
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| Authors: | Navneet Sharma Shiying Liu Lin Tang Jackie Irwin Guoliang Meng Derrick E Rancourt |
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| Affiliation: | (1) Department of Biochemistry & Molecular Biology, Faculty of Medicine, University of Calgary, Heritage Medical Research Building, 3330 Hospital Dr. NW, Calgary, AB, T2N 4N1, Canada |
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| Abstract: | Background We have recently reported the expression of murine Implantation Serine Proteinase genes in pre-implantation embryos (ISP1) and uterus (ISP1 and ISP2). These proteinases belong to the S1 proteinase family and are similar to mast cell tryptases, which function as multimers. |
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