Further evidence for paternal inheritance of mitochondrial DNA in the sheep (Ovis aries) |
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| Authors: | Zhao X Li N Guo W Hu X Liu Z Gong G Wang A Feng J Wu C |
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| Institution: | Department of Animal Science and Technology, China Agricultural University, Beijing 100094, China. |
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| Abstract: | The mitochondrial DNA of 172 sheep from 48 families were typed by using PCR-RFLP, direct amplification of the repeated sequence domain and sequencing analysis. The mitochondrial DNA from three lambs in two half-sib families were found to show paternal inheritance. Our findings provide direct evidence of paternal inheritance of mitochondria DNA in sheep. A total of 12 highly polymorphic microsatellite markers, which mapped on different chromosomes, were employed to type the sheep population to confirm family relationships. Possible mechanisms of paternal inheritance are discussed. |
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