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Completing the sequence of the Sulfolobus solfataricus P2 genome |
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| Authors: | C. W. Sensen Robert L. Charlebois Cynthia Chow Ib Groth Clausen Bruce Curtis W. Ford Doolittle Michel Duguet Gael Erauso Terry Gaasterland Roger A. Garrett Paul Gordon I. Heikamp de Jong Alex C. Jeffries Catherine Kozera Nadine Medina Anick De Moors John van der Oost Hien Phan Mark A. Ragan Margaret E. Schenk Qunxin She Rama K. Singh Niels Tolstrup |
| Affiliation: | National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1 Tel. +1-902-426-7310; Fax +1-902-426-9413 e-mail: sensencw@niji.imb.nrc.ca, CA Canadian Institute for Advanced Research, Evolutionary Biology Program, Canada, CA Dalhousie University, School of Medicine, Department of Biochemistry, Sir Charles Tupper Building, Halifax, NS, Canada B3H 4H7, CA Novo Nordisk A/S, Screening Biotechnology Enzyme Research, Novo Alle Ibmi, DK-2880, Bagsvaerd, Denmark, DK Université Paris Sud, Institut de Genetique et Microbiologie Laboratoire d'Enzymologie des Acides Nucleiques, 15, Rue Georges Clemenceau Batiment 400, FR-91405 Orsay, Cedex, France, FR Wageningen Agricultural University, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, NL-6703 CT, Wageningen, The Netherlands, NL University of Copenhagen, Institute of Molecular Biology, S?lvgade 83H, DK-1307, Copenhagen K, Denmark, DK University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, Ontario, Canada K1N 6N5, CA |
| Abstract: | The Sulfolobus solfataricus P2 genome collaborators are poised to sequence the entire 3-Mbp genome of this crenarchaeote archaeon. About 80% of the genome has been sequenced to date, with the rest of the sequence being assembled fast. In this publication we introduce the genomic sequencing and automated analysis strategy and present intial data derived from the sequence analysis. After an overview of the general sequence features, metabolic pathway studies are explained, using sugar metabolism as an example. The paper closes with an overview of repetitive elements in S. solfataricus. |
| Keywords: | Sulfolobus solfataricus Archaea Genomic sequence MAGPIE |
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