Nitroso-aldicarb induces sister-chromatid exchanges in human lymphocytes in vitro |
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| Authors: | M G González Cid D Loria E Matos |
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| Affiliation: | Instituto de Oncología Angel H. Roffo, Departamento de Investigaciones, Buenos Aires, Argentina. |
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| Abstract: | Nitroso-aldicarb was tested for its ability to induce sister-chromatid exchanges (SCE) and cell-cycle delay in human peripheral blood lymphocytes in vitro. This derivative of aldicarb induced a dose-dependent increase in SCE values per cell. In addition, a slight decrease in the successive mitotic progression of cells in culture was observed. |
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