Effects of differential hypothermia and 5-fluorouracil on C3H mouse mammary tumors: histologic study. |
| |
| Authors: | P Popovic V Popovic D Weathers |
| |
| Affiliation: | Departments of Physiology and Pathology, Emory University, Atlanta, Georgia 30322 USA |
| |
| Abstract: | No regression of mammary tumors of C3H mice was observed in normothermic animals with or without 5-fluorouracil chemotherapy. After prolonged differential hypothermia, histologic changes of necrosis and of cell degeneration were prominent. However, when differential hypothermia of 1 hr and chemotherapy were combined, tumors regressed in 50% of the cases. Histologic changes were more striking and corresponded to the decrease in size of the tumors. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
