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Influence of L-leucine overloading on the level of free amino acids in the diabetic rat] |
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| Authors: | J Grizard M Maciejewska J Prugnaud R Pion |
| Abstract: | Alloxan injection in the rat results in a large increase of branched free amino acids (leucine, isoleucine, valine) in the blood, liver and muscle; it decreases most of the non essential free amino acids in liver. L-leucine administration in the diabetic rat results in a large decrease of plasma corticosterone. It increases free leucine but decreases free isoleucine and valine in blood and muscle. It decreases most of the essential free amino acids in liver. |
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