Model for the supercoiling reaction catalyzed by DNA gyrase |
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| Authors: | P Forterre |
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| Affiliation: | Department of Molecular Virology, The Hebrew University-Hadassah Medical School, Jerusalem, Israel |
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| Abstract: | A hypothesis is presented which suggests that hepatitis B DNA in the Dane particles is only a partial viral genome which becomes integrated into the hepatocyte cellular DNA. The Dane particle DNA must enter a liver cell containing an active e gene, in order to become functional. It is suggested that the partial genome of hepatitis B virus is released from the cellular DNA by the mechanism of “escaping genes”. |
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