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Membrane fusion: caught in a trap
Authors:Short Benjamin  Barr Francis A
Institution:Department of Cell Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18, Martinsried, 82152 Germany. short@biochem.mpg.de
Abstract:SNAREs are small coiled-coil proteins required for specific membrane fusion events in eukaryotic cells. Recent evidence points to the existence of an inhibitory class of SNAREs, i-SNAREs, which prevent incorrect fusions from occurring, adding a further layer of regulation to the process of membrane docking and fusion.
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