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Opposing functions of H2BK120 ubiquitylation and H3K79 methylation in the regulation of pluripotency by the Paf1 complex
Authors:Alexandros Strikoudis  Charalampos Lazaris  Panagiotis Ntziachristos  Aristotelis Tsirigos
Affiliation:1. Department of Pathology, NYU School of Medicine, New York, NY, USA;2. Laura &3. Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY, USA;4. Helen L. &5. Martin S. Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY, USA;6. Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine and Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA;7. Applied Bioinformatics Laboratories, Office of Science &8. Research, NYU School of Medicine, NY, USA
Abstract:
Keywords:Elongation  Embryonic stem cells  Pluripotency  Paf1 complex  Phf5a  Promoter-proximal pausing  Self-renewal network  RNA Polymerase II
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