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Extra-weak chemiluminescence of drugs XV. Method for determining stability of Toki-shakuyaku-san extract granules
Authors:Hideaki Sato  Hideki Hirayama  Takeshi Yamamoto  Yoshimasa Lchio  Fumiaki Ishizawa  Michinao Mizugaki
Abstract:The purpose of the study was to evaluate the quality of Toki-shakuyaku-san extract granules (TJ-23) using chemiluminescence (CL). A linear relationship was obtained between the log value of the CL of TJ-23 and the reaction temperature. An excellent correlation (r= 0.999) was found between the slope of this curve (ΔA) and the colour intensity due to the browning reaction occurring at the early stage of the Maillard reaction.
Keywords:Extra-weak chemiluminescence  Toki-shakuyaku-san extract granules  colour intensity  ferulic acid  paeoniflorin  evaluation of stability
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