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Direct determination of the enantiomeric purity of (R)- and (S)-2-hydroxy-4-phenylbutyric acid
Authors:Zdzis&#x  aw Chilmonczyk,Hanna Ksyci&#x  ska,Hanna Kruszewska,Jacek Cybulski
Affiliation:Zdzisław Chilmonczyk,Hanna Ksycińska,Hanna Kruszewska,Jacek Cybulski
Abstract:The determination of enantiomeric purity of (R)- and (S)-2-hydroxy-4-phenylbutyric acid by chiral HPLC is described. Good resolution has been obtained on covalently bonded L-hydroxyproline saturated with Cu(II) ions. The method makes possible the determination of enantiomeric purity in media containing growing cells. © 1994 Wiley-Liss, Inc.
Keywords:chiral stationary phases  resolution of enantiomers
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