Direct determination of the enantiomeric purity of (R)- and (S)-2-hydroxy-4-phenylbutyric acid |
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Authors: | Zdzis aw Chilmonczyk,Hanna Ksyci ska,Hanna Kruszewska,Jacek Cybulski |
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Affiliation: | Zdzisław Chilmonczyk,Hanna Ksycińska,Hanna Kruszewska,Jacek Cybulski |
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Abstract: | The determination of enantiomeric purity of (R)- and (S)-2-hydroxy-4-phenylbutyric acid by chiral HPLC is described. Good resolution has been obtained on covalently bonded L-hydroxyproline saturated with Cu(II) ions. The method makes possible the determination of enantiomeric purity in media containing growing cells. © 1994 Wiley-Liss, Inc. |
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Keywords: | chiral stationary phases resolution of enantiomers |
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