Basal and ATP-stimulated phosphoinositol metabolism in fusing rat skeletal muscle cells in culture |
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| Authors: | Margit Keresztes Johan Haggblad Edith Heilbronn |
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| Affiliation: | Institute of Biochemistry, Albert Szent-Gy?rgyi Medical University, Szeged, Hungary. |
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| Abstract: | A considerable rise in inositol phosphates was observed at the beginning of myoblast fusion. Extracellular ATP, through P2-purinergic receptors, induced inositol phosphate accumulation before and after fusion; however, no effect of ATP on phosphoinositol levels could be detected during the period of fusion. The possibility of ATP being a fusion signal is discussed. |
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