Dispute on the source of enzymes' catalytic power

The source of enzymes' unusual catalytic power is still a controversial problem. Experimental documentation of enzymatic ability to use their natural dynamic motions in catalytic processes did not end the dispute on the origin of the energy necessary for catalytic work. Thus, it seems that resolution of this problem will only follow given an increase in computer power, such that ab initio simulations of the entire, large protein or ribonucleic acid molecule, engaged in a catalytic process, will be possible.