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Mathematical modeling of tumor therapy with oncolytic viruses: Regimes with complete tumor elimination within the framework of deterministic models
Authors:Artem S Novozhilov  Faina S Berezovskaya  Eugene V Koonin  Georgy P Karev
Institution:(1) National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA;(2) Department of Mathematics, Howard University, 2400 Sixth Str., Washington, D.C. 20059, USA
Abstract:

Background  

Oncolytic viruses that specifically target tumor cells are promising anti-cancer therapeutic agents. The interaction between an oncolytic virus and tumor cells is amenable to mathematical modeling using adaptations of techniques employed previously for modeling other types of virus-cell interaction.
Keywords:
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