Chromatographic separation of a thymus fraction active on lipidic metabolism

Three protein fractions have been obtained from a thymus homogenate of young calf, by a multistep sequence of procedures.Every fraction was administered by intraperitoneal means to a distinct group of rats previously fed, for 21 days, on a diet with high content of dietary fat and cholesterol.The serum values of cholesterol and triglycerids in these animals show a considerable decrease, if compared with the data obtained from control animals, especially with the third chromatographic fraction.