人参皂苷等萜类化合物生物合成途径及HMGR的研究进展

人参皂苷是人参的主要有效成分之一，属典型的萜类化合物。本文对萜类生物合成途径及HMG-CoA还原酶进行了综述。人参皂苷等萜类生物合成分为甲羟戊酸和丙酮酸两种途径，两者都是以异戊烯基焦磷酸为主要的中间产物。大量研究资料表明HMG-CoA还原酶是甲羟戊酸途径的第一个限速关键酶，这对人参皂苷生物合成途径及其调控的深入研究具有一定的参考价值。

Research Progress on Biosynthetic Pathway of Terpenoids Containing Ginsenoside and the HMGR

As a model terpenoid, the ginsenoside is one of Panax ginseng's main effective components. This article has carried on an overview of biosynthetic pathway of terpenoids and the HMG-CoA reductases. The massive research materials indicated that the HMG-CoA reductases is the first key enzyme of the regulation of the mevalonic acid way, which has some reference value to promote the research on the biosynthetic pathway and the regulation of ginsenoside.