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How to build a molecular shock absorber
Authors:McGough A
Affiliation:Verna & Marrs McLean Department of Biochemistry, Baylor College of Medicine, Houston, TX 77030, USA. amcgough@bcm.tmc.edu
Abstract:Newly determined structures of the alpha-helical repeats that make up the key 'rod' domains of spectrin and alpha-actinin - which serve as spacers between their actin-binding domains - have provided important insights into how these proteins function as molecular shock absorbers in cells.
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