Clinical Factors Associated With the Diagnosis and Progression of Diabetic Nephropathy |
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Authors: | Shuang Liang Qian Li Han-Yu Zhu Jian-Hui Zhou Rui Ding Xiang-Mei Chen Guang-Yan Cai |
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Affiliation: | 1. Department of Nephrology, State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, 100853, China 2. Department of Pediatrics, Chinese PLA 309 Hospital, Beijing, 100091, China
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Abstract: | As an important complication of diabetic mellitus, diabetic nephropathy (DN) has been the main cause of end-stage renal disease. It is of great importance to diagnose DN early, and to identify the risk factors of disease progression in order to carry out in-time and effective therapies. Previous literatures have reported the role of several clinical factors in the diagnosis and progression of DN, including age, longer diabetes duration, diabetic retinopathy, higher level of hypertension and HbA1c, and so on. However, the significance of these clinical factors is still controversial and limited. This review aimed to evaluate the values and limitations of these factors in diagnosing and predicting the renal outcome of DN. |
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