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Respiratory virus infection of mice provokes a permanent humoral immune response. |
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| Authors: | L Hyland M Sangster R Sealy C Coleclough |
| Abstract: | We have observed that respiratory virus infection of mice provokes an extremely persistent humoral immune reaction, due to a long-sustained population of antibody-secreting cells in the bone marrow. Theories of humoral immunity that strongly distinguish primary and secondary reactions thus may not adequately describe the immune response to respiratory viruses. |
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