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A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways
Authors:Mikko Taipale  George Tucker  Jian Peng  Irina Krykbaeva  Zhen-Yuan Lin  Brett Larsen  Hyungwon Choi  Bonnie Berger  Anne-Claude Gingras  Susan Lindquist
Institution:1 Whitehead Institute for Biomedical Research, Cambridge, MA 02114, USA;2 Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;3 Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;4 Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Department of Molecular Genetics, University of Toronto, Toronto, ON M5G 1X5, Canada;5 National University of Singapore and National University Health System, Singapore 117597, Singapore;6 Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada;7 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;8 Howard Hughes Medical Institute, Cambridge, MA 02139, USA
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