Nerve-induced secretion of parotid acinar granules in cats |
| |
Authors: | N Emmelin J R Garrett |
| |
Institution: | (1) Institute of Physiology, Lund, Sweden;(2) Department of Oral Pathology, The Rayne Institute, King's College School of Medicine and Dentistry, London, UK;(3) Department of Oral Pathology, The Rayne Institute, King's College School of Medicine and Dentistry, 123 Coldharbour Lane, SE5 9NU London, England |
| |
Abstract: | Summary Electron microscopy of cat parotid glands revealed great heterogeneity in the secretory granules of normal unstimulated acinar cells. Electrical stimulation of the parasympathetic nerve to the gland evoked a copious flow of parotid saliva which was accompanied by an extensive depletion of the secretory granules from the acinar cells. Exocytosis was captured as it was occurring by means of perfusion-fixation, and showed that the events occur in a conventional manner. Stimulation of the sympathetic nerve caused only a very small flow of saliva, and no acinar degranulation was detected. It can be concluded that the parasympathetic secretomotor axons provide the main drive for parotid acinar degranulation in the cat. This contrasts with the rat in which sympathetic impulses provide the main stimulus for parotid acinar degranulation. These dissimilarities serve to emphasise how extensively species differences may influence autonomic responses in salivary glands. |
| |
Keywords: | Salivary secretion Parotid gland Exocytosis Secretory granules Autonomic nerve-stimulation Cat |
本文献已被 SpringerLink 等数据库收录! |
|