Controlled release of bioactive agents |
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Authors: | Joseph Kost Robert Langer |
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Affiliation: | 1. Department of Nutrition and Food Science at the Whitaker College of Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 USA;2. Department of Surgery, Children''s Hospital Medical Center, Boston, MA 02115 USA |
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Abstract: | The use of polymer carriers for the controlled release of bioactive agents including polypeptides is discussed. This paper reviews release mechanisms from polymers, examines applications of these systems, explores approaches to control drug delivery in response to physiological needs, and discusses the impact of controlled drug release with respect to biotechnology. |
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