Reversal of palmitoyl coenzyme A-caused inhibition of glucose-6-phosphate dehydrogenase by polyamines. |
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Authors: | M Mita I Yasumasu |
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Affiliation: | Department of Biology, School of Education, Waseda University, 1-6-1, Nishiwaseda, Shinjuku-ku, Tokyo, 160, Japan |
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Abstract: | Spermine and spermidine released yeast glucose-6-P dehydrogenase from palmitoyl-CoA-induced inhibition. Spermidine was less effective for canceling the inhibition of the enzyme than spermine. Putrescine hardly released the enzyme from the inhibited state. Spermine enhanced slightly the enzyme activity, whereas spermidine and putrescine exerted no activating effect on the enzyme activity. |
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