Steroid derivatives |
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Authors: | J Protiva V Schwarz |
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Institution: | 1. Research Institute of Pharmacy and Biochemistry, 194 04, Prague 9
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Abstract: | Microbial transformation of some steroid 19-hydroxy compounds and 1(10),5-dienes, substituted by a hydroxyl group in position 3, by the action ofProactinomyces globerulus, yielded substances with aromatic A ring. Substrates with 17-keto group underwent simultaneously a partial reduction resulting in the formation of 17β-hydroxyl. |
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