Changes of the Serum Cytokine Contents in Broilers Fed on Diets Supplemented with Nickel Chloride |
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| Authors: | Bangyuan Wu Hengmin Cui Xi Peng Jing Fang Zhicai Zuo Jianying Huang Qin Luo Yubing Deng Hesong Wang Juan Liu |
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| Affiliation: | 1. Key Laboratory of Animal Diseases and Environmental Hazards of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Ya’an, 625014, China
2. College of Veterinary Medicine, Sichuan Agricultural University, Ya’an, Sichuan, China, 625014
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| Abstract: | Cytokines are immunoregulatory proteins which play an important role in the immune system. The purpose of this study was to examine the serum cytokine contents including interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-10 (IL-10), interferon gamma (IFN-γ), and tumor necrosis factor-alpha (TNF-α) induced by dietary nickel chloride in broilers by enzyme-linked immunospecific assay. A total of 240 one-day-old avian broilers were divided into four groups and fed on a corn–soybean basal diet as control diet or the same basal diet supplemented with 300, 600, and 900 mg/kg of nickel chloride. During the experimental period of 42 days, the results showed that the serum IL-2, IL-4, IL-6, IL-10, IFN-γ and TNF-α contents were lower (p?p?
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