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Accuracy and Reproducibility of Adipose Tissue Measurements in Young Infants by Whole Body Magnetic Resonance Imaging
Authors:Jan Stefan Bauer  Peter Benjamin No?l  Christiane Vollhardt  Daniela Much  Saliha Degirmenci  Stefanie Brunner  Ernst Josef Rummeny  Hans Hauner
Affiliation:1Department of Neuroradiology, Technische Universität München, Munich, Germany;2Department of Radiology, Technische Universität München, Munich, Germany;3Else Kröner-Fresenius-Center for Nutritional Medicine, Technische Universität München, Munich, Germany;University of Ulm, GERMANY
Abstract:PurposeMR might be well suited to obtain reproducible and accurate measures of fat tissues in infants. This study evaluates MR-measurements of adipose tissue in young infants in vitro and in vivo.ResultsIn vitro accuracy errors depended on the chosen segmentation procedure, ranging from 5.4% to 76%, while the sequence showed no significant influence. Artificial breathing increased the minimal accuracy error to 9.1%. In vivo reproducibility errors for total fat volume of the sleeping infants ranged from 2.6% to 3.4%. Neither segmentation nor sequence significantly influenced reproducibility.ConclusionWith both cartesian and PROPELLER sequences an accurate and reproducible measure of body fat was achieved. Adequate segmentation was mandatory for high accuracy.
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