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Tetrahydroquinoline sulfonamides as gamma-secretase inhibitors
Authors:Asberom Theodros  Bara Thomas A  Clader John W  Greenlee William J  Guzik Henry S  Josien Hubert B  Li Wei  Parker Eric M  Pissarnitski Dmitri A  Song Lixin  Zhang Lili  Zhao Zhiqiang
Institution:Department of Chemical Research, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. theodros.asberom@spcop.com
Abstract:The development of a novel series of tetrahydroquinoline-derived gamma-secretase inhibitors for the potential treatment of Alzheimer's disease is described.
Keywords:
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