Alkaloids of Uncaria attenuata from Thailand |
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Authors: | Dhavadee Ponglux Tanomjit Supavita Robert Verpoorte David Phillipson |
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Affiliation: | 1. Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 5, Thailand;2. Department of Pharmacognosy, Gorlaeus Laboratories, University of Leiden, Wassenaarseweg 76, Leiden, The Netherlands;3. Department of Pharmacognosy, The School of Pharmacy, 29-39 Brunswick Square, London, WC1N 1AX, U.K. |
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Abstract: | The major alkaloids of a sample of leaves of Uncaria attenuata obtained from Thailand have been identified as the pentacyclic heteroyohimbine alkaloids tetrahydroalstonine, rauniticine and the novel 14-β-hydroxy-3-iso-rauniticine. Evidence for the structure of the new alkaloid was obtained from a study of UV, IR, MS, 1H NMR and 1C NMR spectra. |
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Keywords: | Rubiaceae heteroyohimbine alkaloids tetrahydroalstonine rauniticine |
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