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Alkaloids of Uncaria attenuata from Thailand
Authors:Dhavadee Ponglux  Tanomjit Supavita  Robert Verpoorte  David Phillipson
Affiliation:1. Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 5, Thailand;2. Department of Pharmacognosy, Gorlaeus Laboratories, University of Leiden, Wassenaarseweg 76, Leiden, The Netherlands;3. Department of Pharmacognosy, The School of Pharmacy, 29-39 Brunswick Square, London, WC1N 1AX, U.K.
Abstract:The major alkaloids of a sample of leaves of Uncaria attenuata obtained from Thailand have been identified as the pentacyclic heteroyohimbine alkaloids tetrahydroalstonine, rauniticine and the novel 14-β-hydroxy-3-iso-rauniticine. Evidence for the structure of the new alkaloid was obtained from a study of UV, IR, MS, 1H NMR and 1C NMR spectra.
Keywords:Rubiaceae  heteroyohimbine alkaloids  tetrahydroalstonine  rauniticine
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