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Toddasin,a new dimeric coumarin from Toddalia asiatica |
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| Authors: | Padam N. Sharma Aboo Shoeb Randhir S. Kapil Satya P. Popli |
| Affiliation: | Central Drug Research Institute, Lucknow 226001, India |
| Abstract: | A new dimeric coumarin, named toddasin and possessing a cyclohexene ring with a vinylic side-chain interposed between the two coumarin moieties has been isolated from the roots of Toddalia asiatica. It has been characterized as (E)-8,8′-[1″,4″-dimethyl-3″ -cyclohexen-1″,2″-ylene vinylene]-bis-[5,7-dimethoxycoumarin] (1). The proposed structure is supported by the mass fragmentation of its dihydro derivative (2). |
| Keywords: | Rutaceae roots dimeric coumarin toddasin dihydrotoddasin structural analysis diuretic activity. |
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