Crystallization and preliminary crystallographic data for bovine antithrombin III |
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| Authors: | J P Samama M Delarue L Mourey J Choay D Moras |
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| Institution: | Laboratoire de Cristallographie Biologique, I.B.M.C. du C.N.R.S., Strasbourg, France. |
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| Abstract: | Crystals of bovine antithrombin III were obtained in the presence of metal ions with ammonium sulphate as precipitating agent. Crystals belong to space group P4(1)2(1)2 or P4(3)2(1)2 with cell parameters a = b = 91.4 A, c = 383.1 A; there are two molecules per asymmetric unit. Electrophoresis experiments and amino acid sequence analysis of the N-terminal part of redissolved crystals suggest that the protein molecules are cleaved at the active site. |
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