(1) Institute of Biological Chemistry, Academia Sinica National Taiwan University, P.O.BOX 23-106, Taipei, Taiwan, ROC;(2) Graduate Institute of Biochemical Sciences, National Taiwan University, P.O.BOX 23-106, Taipei, Taiwan, ROC
Abstract:
Summary Doubly enantioselective lipase-catalyzed esterification of racemic acids and alcohols was proceeded in n-hexane. The enantioselectivities of the lipase toward both of racemic substrates were affected reciprocally. It showed that the active site of the lipase was quite flexible.