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Double enantioselective esterification of racemic acids and alcohols by lipase from Candida cylindracea
Authors:Pei-Yeh Chen  Shih-Hsiung Wu  Kung-Tsung Wang
Affiliation:(1) Institute of Biological Chemistry, Academia Sinica National Taiwan University, P.O.BOX 23-106, Taipei, Taiwan, ROC;(2) Graduate Institute of Biochemical Sciences, National Taiwan University, P.O.BOX 23-106, Taipei, Taiwan, ROC
Abstract:Summary Doubly enantioselective lipase-catalyzed esterification of racemic acids and alcohols was proceeded in n-hexane. The enantioselectivities of the lipase toward both of racemic substrates were affected reciprocally. It showed that the active site of the lipase was quite flexible.
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