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Isolation of an Hswl Nav4 Influenza Virus from a Tufted Duck (Aythya fuligula) in Japan
Authors:Misao Tsubokura  Koichi Otsuki  Hiroshi Yamamoto  Yoshihiro Kawaoka  Kuniaki Nerome
Abstract:A hemagglutinating agent was isolated from a tufted duck captured in Lake Shinji, Shimane Prefecture, Japan, and identified as influenza A by double immunodiffusion tests with the antiserum to influenza A virus ribonucleoprotein. The hemagglutinin of the isolate was antigenically related to that of A/New Jersey/8/76 but was not identical with it. The neuraminidase antigen of this Hswl subtype was closely related to that of A/turkey/Ontario/6118/68 and was shown to be Nav4 subtype. After experimental infection of 5-week-old SPF-chickens with the isolate, virus was recovered from various organs including the brain, despite the absence of signs of disease.
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