EFFECT OF PROLACTIN ON THE TADPOLE TAIL FIN. V. STIMULATORY EFFECT OF PROLACTIN ON THE INCORPORATION OF 3H-THYMIDINE INTO DNA OF THE TADPOLE TAIL FIN |
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| Authors: | KATSUTOSHI YOSHIZATO IKUO YASUMASU |
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| Affiliation: | Department of Biology, College of General Education, University of Tokyo, Meguroku, Tokyo 153.;Department of Biology, School of Education, Waseda University, Shinjukuku, Tokyo 160. |
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| Abstract: | DNA content of the tadpole tail fin was increased appreciably by the treatment of animals with bovine prolactin. Incorporation of 3H-thymidine into DNA in the hormone-treated tail fins was remarkably stimulated as compared to the control ones. From the experiment on the effect of prolactin on the DNase activity, it is concluded that prolactin not only stimulates the synthetic parthway, but also suppresses significantly the catabolic one of the DNA metabolism. |
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