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Synthesis and anti-HIV activity of 3′-deoxy-3′-(N-hydroxyamino) analogues of nucleosides |
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| Authors: | Jean M J Tronchet Martina Zs ly Karel Capek and Fabienne de Villedon de Naide |
| Institution: | Institute of Pharmaceutical Chemistry, University of Geneva, Sciences II, CH-1211 Geneva 4 Switzerland |
| Abstract: | 3′-Deoxy analogues of thymidine and uridine bearing a 3′-N-alkyl-(or N-aralkyl) -N-hydroxyamino group either on the  or the β face of the furanose ring have been prepared. One of these (13), exhibited a moderate anti-HIV activity. |
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