A cytokine in the Drosophila stress response |
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Authors: | Hultmark Dan Ekengren Sophia |
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Affiliation: | Ume? Centre for Molecular Pathogenesis, Ume? University, S-901 87, Ume?, Sweden. |
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Abstract: | The fruit fly, Drosophila melanogaster, has become a popular tool for studying immediate reactions to environmental hazards, such as the heat shock and innate immune responses. In mammals, protective responses to infections and other insults are coordinated by a complex network of cytokines that mediate cell-to-cell signaling. By contrast, the corresponding heat shock and innate immune responses in Drosophila have usually been regarded as cell-autonomous processes. However, in this issue of Developmental Cell, show that cytokines do play a role in mediating an acute phase response in this organism. |
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