Polynucleotide kinase mutant of bacteriophage T4 |
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| Authors: | Voon Loong Chan and Kaney Ebisuzaki |
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| Affiliation: | (1) Cancer Research Laboratory, University of Western Ontario, London, Ontario, Canada |
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| Abstract: | Summary We report the isolation and biological properties of two T4 phage mutants which are deficient in polynucleotide kinase. These two mutants are wild type with respect to replication, genetic recombination and DNA repair (as measured by sensitivity to UV irradiation,  -irradiation and 32P decay). These negative results suggest that this phage-induced enzyme is not a critical factor in DNA metabolism. |
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