Human placental and intestinal alkaline phosphatase genes map to 2q34-q37 |
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| Authors: | C A Griffin M Smith P S Henthorn H Harris M J Weiss M Raducha B S Emanuel |
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| Institution: | Department of Pediatrics, Children's Hospital of Philadelphia, PA 19104. |
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| Abstract: | The alkaline phosphatases comprise a multigene enzyme family that hydolyze phosphate esters and are widely distributed in nature. Three main classes have been isolated from humans, the placental, intestinal, and liver/bone/kidney forms. We have mapped the placental and intestinal alkaline phosphatase genes to 2q34-q37 by using chromosomal in situ hybridization and a somatic-cell hybrid panel. |
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