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Hexafluoroacetone as protecting and activating reagent: Site-selective functionalization of iminodiacetic acid |
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| Authors: | T. Rühl C. Böttcher L. Hennig K. Burger |
| Affiliation: | (1) Organisch-Chemisches Institut der Universität Leipzig, Leipzig, Germany |
| Abstract: | Summary. Hexafluoroacetone was applied as a bidentate protecting and activating agent for the syntheses of RGD-peptide mimetics starting from iminodiacetic acid in solution and on solid phase. |
| Keywords: | : Iminodiacetic acid – Hexafluoroacetone – Integrins – Site selective functionalization – Solid phase synthesis – Wang resin – PEGA resin – Affinity labeling |
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