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Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
Institution:1. McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G 1L7, Canada;2. Toronto General Hospital Research Institute, University Health Network, Toronto, ON M5G 1L7, Canada;3. Deparment of Physiology, University of Toronto, Toronto, ON M5S 1A8, Canada;4. Institute of Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada;5. Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON M5G 1E2, Canada;6. Laboratory of Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada;7. Heart & Stroke/Richard Lewar Centre of Excellence, University of Toronto, Toronto, ON M5S 3H2, Canada
Abstract:
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  • Keywords:islet transplantation  embryonic stem cells  endothelial cells  microvessels  pancreatic progenitors  subcutaneous  type 1 diabetes  beta cells  regenerative medicine  vascularization
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