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Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
Affiliation:1. Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland;2. Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany;3. Department of Physiology, University of Zurich, Zurich, Switzerland;4. Institute for Molecular Cancer Research, University of Zurich, Zurich, Switzerland;5. Department of Quantitative Biomedicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland;6. Institute of Molecular Systems Biology, Federal Institute of Technology Zurich, Zurich, Switzerland;7. Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA;8. PharmaBiome AG, Zurich, Switzerland;9. Department of Immunology, University Hospital Zurich, University of Zurich, Zurich, Switzerland;10. Department of Medical Oncology and Hematology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
Abstract:
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  • Keywords:cancer  colorectal cancer  tumor therapy  Clostridiales  gut microbiota  immunotherapy  tumor models  solid tumors
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