Development of phosphodiesterase activity in the chick retina |
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| Authors: | G J Chader R T Fletcher D A Newsome |
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| Affiliation: | Laboratory of Vision Research, National Eye Institute, National Institutes of Health, U.S. Department of Health, Education, and Welfare, Bethesda, Maryland 20014 USA |
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| Abstract: | Significant cyclic GMP phosphodiesterase activity is apparent in the early stages of development of the chick neural retina. By day 8, specific activity drops by approximately two-thirds. After day 14, a sharp rise in activity is observed, continuing through the time of hatching. Cyclic AMP phosphodiesterase activity is considerably lower and does not markedly change over the embryonic period. |
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