Newly observed binding mode in pancreatic ribonuclease. |
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Authors: | C F Aguilar P J Thomas A Mills D S Moss R A Palmer |
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Affiliation: | Crystallography Department, Birkbeck College, University of London, U.K. |
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Abstract: | Dinucleotides containing guanine, when soaked into crystals of bovine pancreatic ribonuclease, have been found to bind in an unexpected manner, quite unlike interpretations of earlier X-ray diffraction studies. This finding has prompted a reexamination of three mononucleotide-RNase complexes from this laboratory resulting in a re-interpretation of the complex that involved a guanine mononucleotide. |
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