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Newly observed binding mode in pancreatic ribonuclease.
Authors:C F Aguilar  P J Thomas  A Mills  D S Moss  R A Palmer
Affiliation:Crystallography Department, Birkbeck College, University of London, U.K.
Abstract:Dinucleotides containing guanine, when soaked into crystals of bovine pancreatic ribonuclease, have been found to bind in an unexpected manner, quite unlike interpretations of earlier X-ray diffraction studies. This finding has prompted a reexamination of three mononucleotide-RNase complexes from this laboratory resulting in a re-interpretation of the complex that involved a guanine mononucleotide.
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