Testing the additional predictive value of high-dimensional molecular data |
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Authors: | Anne-Laure Boulesteix Torsten Hothorn |
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Institution: | (1) Department of Medical Informatics, Biometry and Epidemiology, University of Munich, Marchioninistr, 15, D-81377 Munich, Germany;(2) Department of Statistics, University of Munich, Ludwigstr 33, D-80539 Munich, Germany |
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Abstract: | Background While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction
or diagnosis purposes for about ten years in biomedical research, the question of the additional predictive value of such
data given that classical predictors are already available has long been under-considered in the bioinformatics literature. |
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Keywords: | |
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