胸腹水标本分离菌构成与耐药性

目的探讨胸腹水标本分离菌构成及其耐药性。方法对2004年1月至2005年12月临床送检胸腹水标本细菌培养和药敏试验资料进行回顾性分析。结果(1)1 682例胸腹水标本细菌培养阳性276例,阳性16.4%,检出病原菌327株,以铜绿假单胞菌、金黄色葡萄球菌、表皮葡萄球菌、大肠埃希菌最多见。(2)胸水标本G 球菌与G-杆菌构成比接近,腹水标本G-杆菌占优势(63.5%)。(3)4种主要病原菌对链霉素、庆大霉素、氨苄西林、羧苄西林、克林霉素耐药,亚胺培南、舒普深、美洛西林则显示敏感,其他抗菌药物呈现不同程度的耐药。结论加强腹水标本的细菌学检查,依据药敏试验合理使用抗菌药物,对胸腔感染的诊断与治疗具有重要价值。

Constitution and their drug resistance of clinical isolated bacteria in hydrothorax-peritoneum samples

Objective To investigate the bacteriological feature and drug-fast of bacteria in hydrothorax-peritoneum.Method The retrospective analysis of bacteria culture and drug-sensitive test in hydrothorax-peritoneum preparation collected from 2004.1 to 2005.12 was done.Results(1)The hydrothorax-peritoneum preparation were 1682 cases,the bacteria culture positive were 276 cases,positive rate was 16.4%,327 strains pathogenic bacteria were found in which P.aesuginosa,S.aurus,S.epidermidis,E.coli were seen most commonly.(2)The composition of G coccus and G-bacillus were almost equivalent in hydrothorax.G-bacillus's percentage was high(63.5%) in hydroperitoneum.(3)Four pathogenic bacteria showed drug-fast to Streptomycin,Gentamycin,Ampicillin,Carbenicillin,Clindamycin,but sensitive to Imipenem,Sulperazon,Mezlacillin.The others were drug fast against clinical isolates at different degree.Conclusions The bacteriological examination of hydrothorax-peritoneum must be done.Selecting bacteria-sensitive drug has a important value to diagnosing and treating infection of thoracic and abdominal cavity.