Influence of endogenous glutathione level on X-ray induced cell cycle delay in human lymphocytes |
| |
| Authors: | Ray S Chatterjee A |
| |
| Institution: | Genetics Laboratory, Department of Biotechnology and Bioinformatics, North-Eastern Hill University, Shillong, India. |
| |
| Abstract: | Here, induction of chromosomal aberration after X-irradiation and the pattern of cell cycle kinetics have been investigated in human lymphocytes, after exogenous addition of reduced glutathione or by depleting levels of reduced glutathione endogenously. Involvement of cell cycle regulator proteins such as p53 and p21 has been investigated to elucidate their role in induction of delay in cell cycle progression after irradiation. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
