Dynamics of continuous stirred-tank biochemical reactor utilizing inhibitory substrate

The model of a continuous-stirred tank biochemical reactor was developed in which the instant uptake rate of substrate was used. The solutions of the model found for the oxidation of phenol by Pseudomonas putida fitted the experimental data better than the results obtained from the models cited in the literature. The model enables control of the culture parameters so that the unwanted washout of the biomass from the bioreactor can be avoided. A review of the models cited in the literature is also presented.